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Article

Vitamin D receptor and calcium-sensing receptor polymorphisms and colorectal cancer survival in the Newfoundland population.

British journal of cancer - 5 Sept 2017

Zhu Yun, Wang Peizhong Peter, Zhai Guangju, Bapat Bharati, Savas Sevtap, Woodrow Jennifer R, Sharma Ishor, Li Yuming, Zhou Xin, Yang Ning, Campbell Peter T, Dicks Elizabeth, Parfrey Patrick S, Mclaughlin John R

Abstract excerpt

BACKGROUND: Increased serum levels of vitamin D and calcium have been associated with lower risks of colorectal cancer (CRC) incidence and mortality. These inverse associations may be mediated by the vitamin D receptor (VDR) and the calcium-sensing receptor (CASR). We investigated genetic variants in VDR and CASR for their relevance to CRC prognosis. METHODS: A population-based cohort of 531 CRC patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasm Recurrence, Local

Share to Newfoundland and Labrador

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Share to Receptors, Calcitriol

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Source

Open in PubMed Open full text

Identifiers

PMID: 28765616
DOI: 10.1038/bjc.2017.242
PMCID: PMC5589991

Genes

CASR
VDR

Variants

rs10222633
rs10222633

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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