Article
Interactions between genetic variants in the adiponectin, adiponectin receptor 1 and environmental factors on the risk of colorectal cancer.
PloS one - 1 Jan 2011
Liu Li, Zhong Rong, Wei Sheng, Yin Jie-Yun, Xiang Hao, Zou Li, Chen Wei, Chen Ji-Gui, Zheng Xia-Wen, Huang Li-Juan, Zhu Bei-Bei, Chen Quan, Duan Sheng-Yu, Rui Rui, Yang Bei-Fang, Sun Jing-Wen, Xie Duo-Shuang, Xu Yi-Hua, Miao Xiao-Ping, Nie Shao-Fa
Abstract excerpt
BACKGROUND: Metabolic syndrome traits play an important role in the development of colorectal cancer. Adipokines, key metabolic syndrome cellular mediators, when abnormal, may induce carcinogenesis. METHODOLOGY/PRINCIPAL FINDINGS: To investigate whether polymorphisms of important adipokines, adiponectin (ADIPOQ) and its receptors, either alone or in combination with environmental factors, are implicated in...
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