Article
Circulating Lipoprotein Lipids, Apolipoproteins and Ischemic Stroke.
Annals of neurology - 1 Dec 2020
Yuan Shuai, Tang Bowen, Zheng Jie, Larsson Susanna C
Abstract excerpt
OBJECTIVE: We conducted a Mendelian randomization (MR) study to disentangle the comparative effects of lipids and apolipoproteins on ischemic stroke. METHODS: Single-nucleotide polymorphisms associated with low- and high-density lipoprotein (LDL and HDL) cholesterol, triglycerides, and apolipoprotein A-I and B (apoA-I and apoB) at the level of genomewide significance (p < 5 × 10-8 ) in the UK Biobank were used as...
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