Article

Shared genetic architecture and causal pathways between attention deficit hyperactivity disorder and restless legs syndrome

2024-06-21

Abstract excerpt

Previous studies have revealed a significant overlap between ADHD and RLS populations, with shared pathological mechanisms such as dopaminergic function and iron metabolism deficits. However, the genetic mechanisms underlying these connections remain unclear. In our study, we conducted a genome-wide genetic correlation analysis to confirm a shared genetic structure between ADHD and RLS. We identified five pleiotro...

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Literature Corpus work: 077247f3-732b-5e9b-994d-2a7dab2d4555
DOI: 10.1101/2024.06.20.24309235

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