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Article

Transcriptome-wide association study for restless legs syndrome identifies new susceptibility genes.

Communications biology - 10 Jul 2020

Akçimen Fulya, Sarayloo Faezeh, Liao Calwing, Ross Jay P, Oliveira Rachel De Barros, Dion Patrick A, Rouleau Guy A

Abstract excerpt

Restless legs syndrome (RLS) is a common neurological condition, with a prevalence of 5-15% in Central Europe and North America. Although genome-wide association studies (GWAS) have identified some common risk regions for RLS, the causal genes have yet to be fully elucidated. We conducted a transcriptome-wide association study involving 15,126 RLS cases and 95,725 controls, from the most recent meta-analysis of...

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Identifiers

PMID: 32651461
DOI: 10.1038/s42003-020-1105-z
PMCID: PMC7351781

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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