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Article

RUNX1 mutation has no prognostic significance in paediatric AML: a retrospective study of the AML-BFM study group.

Leukemia - 1 Jul 2023

Sendker Stephanie, Awada Amani, Domagalla Sophia, Sendker Michael, Orhan Eser, Hoffmeister Lina Marie, Antoniou Evangelia, Niktoreh Naghmeh, Reinhardt Dirk, von Neuhoff Nils, Schneider Markus

Abstract excerpt

In acute myeloid leukaemia (AML) RUNX1 mutation is characterised by certain clinicopathological features with poor prognosis and adverse risk by the European LeukemiaNet recommendation. Though initially considered as provisional category, the recent World Health Organisation (WHO) classification of 2022 removed RUNX1-mutated AML from the unique entity. However, the significance of RUNX1 mutation in paediatric AML...

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Identifiers

PMID: 37188777
DOI: 10.1038/s41375-023-01919-8
PMCID: PMC10317839

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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