Article
Investigations of the prognostic value of RUNX1 mutation in acute myeloid leukemia patients: Data from a real-world study.
Leukemia research - 1 Apr 2024
Wan Chao-Ling, Huang Yuan-Hong, Huang Si-Man, Xu Yan-Li, Tan Kai-Wen, Yan-Qiu, Shen Xiang-Dong, Ge Shuai-Shuai, Cao Han-Yu, Li Yan-Yan, Liu Song-Bai, Qi Jia-Jun, Dai Hai-Ping, Xue Sheng-Li
Abstract excerpt
RUNX1 is one of the recurrent mutated genes in newly diagnosed acute myeloid leukemia (AML). Although historically recognized as a provisional distinct entity, the AML subtype with RUNX1 mutations (AML-RUNX1mut) was eliminated from the 2022 WHO classification system. To gain more insight into the characteristics of AML-RUNX1mut, we retrospectively analyzed 1065 newly diagnosed adult AML patients from the First...
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