Article
[Clinical characteristics of RUNX1-mutated acute myeloid leukemia patients].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 14 Jan 2026
Dong Y X, Dai W J, Zhang W Q, Xie B B, Zhang Q, Dong Y, Qin H, Zhai Z M, Tao Q S, Tao L L
Abstract excerpt
We retrospectively analyzed the RUNX1 mutation status and clinical characteristics of 323 newly diagnosed acute myeloid leukemia (AML) patients treated in the Second Affiliated Hospital of Anhui Medical University from February 2018 to May 2023. The mutation rate of RUNX1 in AML patients was 11.5% with a median mutation frequency of 40.4%. RUNX1 mutations often coexisted with other mutations, such as ASXL1, but...
Topics
- Humans
- Core Binding Factor Alpha 2 Subunit
- Nucleophosmin
- Leukemia, Myeloid, Acute
- Mutation
- Middle Aged
- Female
- Male
- Retrospective Studies
- Prognosis
- Aged
- Adult
- Adolescent
- Repressor Proteins
- Young Adult