Clinico-pathologic characteristics and outcomes of the World Health Organization (WHO) provisional entity de novo acute myeloid leukemia with mutated RUNX1.

doi:10.1038/s41379-020-0531-2

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Clinico-pathologic characteristics and outcomes of the World Health Organization (WHO) provisional entity de novo acute myeloid leukemia with mutated RUNX1.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Sept 2020

Quesada Andrés E, Montalban-Bravo Guillermo, Luthra Rajyalakshmi, Patel Keyur P, Sasaki Koji, Bueso-Ramos Carlos E, Khoury Joseph D, Routbort Mark J, Bassett Roland, Hidalgo-Lopez Juliana E, Zhao Chong, Lin Pei, Loghavi Sanam, Ok Chi Y, Kadia Tapan, DiNardo Courtney D, Kantarjian Hagop, Garcia-Manero Guillermo, Kanagal-Shamanna Rashmi

Abstract excerpt

We studied the characteristics of the provisional category de novo acute myeloid leukemia (AML) with mutated RUNX1 (AML-RUNX1mut) proposed by the World Health Organization (WHO). Until now, most published studies have combined de novo and secondary AML-RUNX1mut. We compared the clinicopathologic characteristics and outcomes of WHO-defined de novo AML-RUNX1mut with de novo AML without RUNX1 alterations...

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PMID: 32238878
DOI: 10.1038/s41379-020-0531-2

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