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Article

Expression in skin biopsies supports genetic evidence linking CAMKK2, P2X7R and P2X4R with HIV-associated sensory neuropathy.

Journal of neurovirology - 1 Jun 2023

Gaff Jessica, Octaviana Fitri, Jackaman Connie, Kamerman Peter, Papadimitriou John, Lee Silvia, Mountford Jenjira, Price Patricia

Abstract excerpt

HIV-associated sensory neuropathy (HIV-SN) affects 14-38% of HIV+ individuals stable on therapy with no neurotoxic drugs. Polymorphisms in CAMKK2, P2X7R and P2X4R associated with altered risk of HIV-SN in Indonesian and South African patients. The role of CaMKK2 in neuronal repair makes this an attractive candidate, but a direct role for any protein is predicated on expression in affected tissues. Here, we...

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Identifiers

PMID: 37166584
DOI: 10.1007/s13365-023-01134-2
PMCID: PMC10404215

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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