Article
Brief Report: Demographic and Genetic Associations With Markers of Small and Large Fiber Sensory Neuropathy in HIV Patients Treated Without Stavudine.
Journal of acquired immune deficiency syndromes (1999) - 15 Dec 2020
Safri Ahmad Yanuar, Gaff Jessica, Octaviana Fitri, Setiawan Denise Dewanto, Imran Darma, Cherry Catherine L, Laws Simon M, Price Patricia
Abstract excerpt
Neurotoxic antiretroviral therapy (ART) such as stavudine has been now replaced with safer therapies, reducing the prevalence of neuropathy from 34% to 15% in HIV+ Indonesians. However, it is unclear whether the residual cases display damage to small or large nerve fibers and whether both are influenced by known risk factors, including alleles of CAMKK2 associated with neuropathy in HIV patients. The encoded...
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