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Article

Role of TNF block genetic variants in HIV-associated sensory neuropathy in black Southern Africans.

European journal of human genetics : EJHG - 1 Mar 2015

Wadley Antonia L, Hendry Liesl M, Kamerman Peter R, Chew Constance S N, Price Patricia, Cherry Catherine L, Lombard Zané

Abstract excerpt

HIV-associated sensory neuropathy (HIV-SN) is a common neurological complication of HIV infection. The TNF block is a region within the central MHC that contains many immunoregulatory genes. Polymorphisms and haplotypes of the TNF block have been associated with increased risk of HIV-SN in Asians and whites. Here we investigated genetic associations with HIV-SN in 342 black Southern Africans (190 cases and 152...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24896147
DOI: 10.1038/ejhg.2014.104
PMCID: PMC4326702

Genes

TNF
LTA
NFKBIL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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