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Article

Brief Report: Polymorphisms in CAMKK2 may Influence Domain-Specific Neurocognitive Function in HIV+ Indonesians Receiving ART.

Journal of acquired immune deficiency syndromes (1999) - 1 Jan 2022

Gaff Jessica, Estiasari Riwanti, Diafiri Dinda, Halstrom Samuel, Kamerman Peter, Price Patricia

Abstract excerpt

BACKGROUND: Despite effective antiretroviral therapy (ART), milder forms of HIV-associated neurocognitive disorders remain prevalent and are characterized by neuroinflammation, synaptic dysfunction, and neuronal loss. METHODS: We explore associations between neurocognitive impairment in HIV+ Indonesians and 17 polymorphisms in adjacent genes involved in inflammation and neuronal growth/repair pathways, P2X4R and...

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PMID: 34878439
DOI: 10.1097/QAI.0000000000002819

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