Article
TNF-Block Genotypes Influence Susceptibility to HIV-Associated Sensory Neuropathy in Indonesians and South Africans.
International journal of molecular sciences - 7 Jan 2020
Gaff Jessica, Octaviana Fitri, Pillay Prinisha, Mbenda Huguette Gaelle Ngassa, Ariyanto Ibnu A, Gan June Anne, Cherry Catherine L, Kamerman Peter, Laws Simon M, Price Patricia
Abstract excerpt
HIV-associated sensory neuropathy (HIV-SN) is a disabling complication of HIV disease and antiretroviral therapies (ART). Since stavudine was removed from recommended treatment schedules, the prevalence of HIV-SN has declined and associated risk factors have changed. With stavudine, rs1799964*C (TNF-1031) associated with HIV-SN in Caucasians and Indonesians but not in South Africans. Here, we investigate...
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