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Article

HIV-associated sensory polyneuropathy and neuronal injury are associated with miRNA–455-3p induction

5 Dec 2018

Abstract excerpt

Symptomatic distal sensory polyneuropathy (sDSP) is common and debilitating in people with HIV/AIDS, leading to neuropathic pain, although the condition's cause is unknown. To investigate biomarkers and associated pathogenic mechanisms for sDSP, we examined plasma miRNA profiles in HIV/AIDS patients with sDSP or without sDSP in 2 independent cohorts together with assessing related pathogenic effects. Several...

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PMID: 30518697
DOI: 10.1172/jci.insight.122450

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