Article
Polymorphisms in CAMKK2 may predict sensory neuropathy in African HIV patients.
Journal of neurovirology - 1 Aug 2016
Goullee Hayley, Wadley Antonia L, Cherry Catherine L, Allcock Richard J N, Black Michael, Kamerman Peter R, Price Patricia
Abstract excerpt
HIV-associated sensory neuropathy (HIV-SN) is the most common neurological condition associated with HIV. HIV-SN has characteristics of an inflammatory pathology caused by the virus itself and/or by antiretroviral treatment (ART). Here, we assess the impact of single-nucleotide polymorphisms (SNPs) in a cluster of three genes that affect inflammation and neuronal repair: P2X7R, P2X4R and CAMKK2. HIV-SN status was...
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