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Article

The Frequency of Specific KRAS Mutations, and Their Impact on Treatment Choice and Survival, in Patients With Metastatic Colorectal Cancer.

The oncologist - 3 Oct 2023

Fernández Montes Ana, Alonso Orduña Vicente, Asensio Martínez Elena, Rodríguez Salas Nuria, Torres Esperanza, Cacho Lavín Diego, Rodríguez Alonso Rosa María, Falcó Esther, Oliva Joan Carles, Cirera Lluis, García Gómez Jesus, Pericay Carles

Abstract excerpt

BACKGROUND: Patients with metastatic colorectal cancer (mCRC) and KRAS mutations have a poor prognosis, seemingly dependent on the location of the mutation. This multicenter, retrospective, cohort study assessed the frequency and prognostic value of specific KRAS mutation codon locations in mCRC patients, and survival outcomes in relation to treatment. MATERIALS AND METHODS: Data from mCRC patients treated in 10...

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Identifiers

PMID: 37141400
DOI: 10.1093/oncolo/oyad117
PMCID: PMC10546812

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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