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Article

Prognostic Value of KRAS Mutations in Colorectal Cancer Patients

7 Jul 2022

Abstract excerpt

Colorectal cancer (CRC) remains a major public health issue. The detection of parameters that affect CRC prognosis is of great significance. KRAS mutations, play a crucial role in tumorigenesis with a strong predictive value. KRAS-mutated stage-IV CRC patients gain no benefit of the anti-EGFR therapy. The KRAS G12C mutation subtype is under investigation for treatment regimens. The present study aimed to detect...

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PMID: 35884381
DOI: 10.3390/cancers14143320

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