Effect of KRAS and BRAF mutations in metastatic colorectal cancer patients: A systematic review and meta-analysis based on tumor sidedness and KRAS subtypes.

doi:10.3233/HAB-210451

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Article

Effect of KRAS and BRAF mutations in metastatic colorectal cancer patients: A systematic review and meta-analysis based on tumor sidedness and KRAS subtypes.

Human antibodies - 1 Jan 2021

Saravani Khadijeh, Salarzaei Morteza, Parooie Fateme

Abstract excerpt

INTRODUCTION: Metastatic or recurrent colorectal cancer (MRCRC) has a poor prognosis. The aim of the present meta-analysis was to assess the prevalence of different subtypes of KRAS mutation and BRAF mutation in metastatic CRC patients, and evaluate the relationship between the tumor sidedness an...

Topics

Colorectal Neoplasms
Humans
Mutation
Neoplasm Recurrence, Local
Proto-Oncogene Proteins B-raf
Proto-Oncogene Proteins p21(ras)

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