Article
Clinical and prognostic implications of RAS mutations in metastatic colorectal cancer.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico - 1 Jun 2026
Ataca Evrim, Keskinkilic Merve, Sarioglu Sulen, Basbinar Yasemin, Yavuzsen Tugba
Abstract excerpt
PURPOSE: RAS mutations play a critical role in the pathogenesis and progression of colorectal cancer. This study aimed to evaluate the clinical and pathological characteristics associated with RAS mutation status and to investigate its prognostic value in patients with metastatic colorectal cancer. METHODS: This retrospective study included 446 adult patients with metastatic colorectal cancer followed at Dokuz...
Topics
- Humans
- Colorectal Neoplasms
- Female
- Male
- Mutation
- Middle Aged
- Retrospective Studies
- Prognosis
- Aged
- Proto-Oncogene Proteins p21(ras)
- Adult
- Aged, 80 and over
- Survival Rate
- Lung Neoplasms
- ErbB Receptors