Article
Impact of KRAS mutation on outcome of patients with metastatic colorectal cancer.
Hepato-gastroenterology - 1 Oct 2014
Chang Yu-Yao, Lin Jen-Kou, Lin Tzu-Chen, Chen Wei-Shone, Jeng Kai-Jiang, Yang Shung-Haur, Wang Huann-Sheng, Lan Yuan-Tzu, Lin Chun-Chi, Liang Wen-Yih, Chang Shih-Ching
Abstract excerpt
BACKGROUND/AIMS: KRAS mutation is present in 30%-50% of colorectal cancers and is associated with the inefficacy of anti-epidermal growth factor receptor therapy, while the impact of KRAS on survival is seldom discussed. The aim of this study was to elucidate the impact of KRAS status on the survival of patients with metastatic colorectal cancer. METHODOLOGY: Two hundred and one patients with metastatic...
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