Article
Genetic Characterization of Ovarian Tumor Tissues from Patients with Epithelial Ovarian Cancer in a Philippine Tertiary Hospital: A Descriptive Study.
Asian Pacific journal of cancer prevention : APJCP - 1 Apr 2023
Lintao Ryan C V, Padua Ana Joy P, Nakura Yukiko, Llamas-Clark Erlidia F, Yanagihara Itaru
Abstract excerpt
OBJECTIVE: This study identified genetic variations in ovarian tumor specimens from Filipino epithelial ovarian cancer (EOC) patients using next-generation sequencing. METHODS: Genomic DNA was isolated from formalin-fixed paraffin-embedded ovarian specimens from 8 chemosensitive and 8 chemoresistant EOC patients. Targeted next-generation sequencing was done to identify mutations in hotspot regions of common...
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