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Article

Identification and clinical significance of somatic oncogenic mutations in epithelial ovarian cancer.

Journal of ovarian research - 6 Oct 2021

Watanabe Takafumi, Nanamiya Hideaki, Endo Yuta, Kojima Manabu, Nomura Shinji, Furukawa Shigenori, Soeda Shu, Tamura Hirosumi, Ryufuku Masae, Tanaka Daisuke, Isogai Takao, Imai Jun-Ichi, Watanabe Shinya, Fujimori Keiya

Abstract excerpt

OBJECTIVE: Epithelial ovarian cancer (EOC) is a heterogeneous disease with diverse clinicopathological features and behaviors, and its heterogeneity may be concerned with the accumulation of multiple somatic oncogenic mutations. The major goals of this study are to systematically perform the comprehensive mutational profiling in EOC patients, and investigate the associations between somatic mutations and...

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Identifiers

PMID: 34615547
DOI: 10.1186/s13048-021-00876-z
PMCID: PMC8496016

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