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Article

High throughput interrogation of somatic mutations in high grade serous cancer of the ovary.

PloS one - 1 Jan 2011

Matulonis Ursula A, Hirsch Michelle, Palescandolo Emanuele, Kim Eejung, Liu Joyce, van Hummelen Paul, MacConaill Laura, Drapkin Ronny, Hahn William C

Abstract excerpt

BACKGROUND: Epithelial ovarian cancer is the most lethal of all gynecologic malignancies, and high grade serous ovarian cancer (HGSC) is the most common subtype of ovarian cancer. The objective of this study was to determine the frequency and types of point somatic mutations in HGSC using a mutation detection protocol called OncoMap that employs mass spectrometric-based genotyping technology....

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Source

Open in PubMed Open full text

Identifiers

PMID: 21931712
DOI: 10.1371/journal.pone.0024433
PMCID: PMC3169600

Genes

EGFR
KIT
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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