An Analysis of Genetic Polymorphisms in 76 Genes Related to the Development of Ovarian Tumors of Different Aggressiveness.

doi:10.3390/ijms252010876

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Article

An Analysis of Genetic Polymorphisms in 76 Genes Related to the Development of Ovarian Tumors of Different Aggressiveness.

International journal of molecular sciences - 10 Oct 2024

Szafron Laura A, Sobiczewski Piotr, Dansonka-Mieszkowska Agnieszka, Kupryjanczyk Jolanta, Szafron Lukasz M

Abstract excerpt

Borderline ovarian tumors (BOTS) are rare neoplasms of intermediate aggressiveness between cystadenomas and low-grade ovarian cancers (lgOvCa), which they share some molecular resemblances with. In contrast to the most frequent and well-described high-grade ovarian carcinomas (hgOvCa), the molecular background of BOTS and lgOvCa is less thoroughly characterized. Here, we aimed to analyze genetic variants in...

Topics

Female
Humans
Ovarian Neoplasms
Middle Aged
Biomarkers, Tumor
Mutation
Adult
Polymorphism, Genetic
Aged
Proto-Oncogene Proteins B-raf

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PMID: 39456660
DOI: 10.3390/ijms252010876
PMCID: PMC11507582

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