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Germline and somatic mutations of multi-gene panel in Chinese patients with epithelial ovarian cancer: a prospective cohort study

31 Aug 2019

Abstract excerpt

BACKGROUND: Multiple targeted gene sequencing is seldom performed in both germline and somatic testing for ovarian cancer. This study is to evaluate the specific genetic alterations, including both somatic and germline mutations, in Chinese patients with epithelial ovarian cancer (EOC) in a prospective cohort study. MATERIALS AND METHODS: Mutations in a customed 21-gene panel that included BRCA1, BRCA2, and 19...

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PMID: 31472684
DOI: 10.1186/s13048-019-0560-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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