Molecular and clinicopathologic characterization of pediatric histiocytoses.

doi:10.1002/ajh.26938

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Article

Molecular and clinicopathologic characterization of pediatric histiocytoses.

American journal of hematology - 1 Jul 2023

Hélias-Rodzewicz Zofia, Donadieu Jean, Terrones Nathalie, Barkaoui Mohamed-Aziz, Lambilliotte Anne, Moshous Despina, Thomas Caroline, Azarnoush Saba, Pasquet Marlène, Mansuy Ludovic, Aladjidi Nathalie, Jeziorski Eric, Marec-Berard Perrine, Gilibert-Yvert Marion, Spiegel Alexandra, Saultier Paul, Pellier Isabelle, Pagnier Anne, Pertuisel Sophie, Poiree Maryline, Bodet Damien, Millot Frédéric, Isfan Florentina, Stephan Jean-Louis, Leruste Amaury, Rigaud Charlotte, Filhon Bruno, Carausu Liana, Reguerre Yves, Kieffer Isabelle, Brichard Bénédicte, Ben Jannet Rim, Bakari Mariama, Idbaih Ahmed, Bodemer Christine, Cohen-Aubart Fleur, Haroche Julien, Tazi Abdellatif, Boudjemaa Sabah, Fraitag Sylvie, Emile Jean-François, Heritier Sébastien

Abstract excerpt

The spectrum of somatic mutations in pediatric histiocytoses and their clinical implications are not fully characterized, especially for non-Langerhans cell histiocytosis (-LCH) subtypes. A cohort of 415 children with histiocytosis from the French histiocytosis registry was reviewed and analyzed...

Topics

Humans
Child
Histiocytosis, Langerhans-Cell
Proto-Oncogene Proteins B-raf
Erdheim-Chester Disease
Mutation
Exons

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PMID: 37115038
DOI: 10.1002/ajh.26938

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-37115038-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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