Article
[An overview of histiocytosis].
[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Jan 2022
Tojo Arinobu
Abstract excerpt
Histiocytosis is a syndrome characterized by fever, pain, and other symptoms caused by the neoplastic proliferation of atypical cells of the macrophage-dendritic cell lineage and surrounding inflammatory cell infiltration. The diagnosis is confirmed by the immune-histological features of biopsied specimens. From this viewpoint, histiocytosis is divided into Langerhans cell histiocytosis (LCH)...
Topics
- Erdheim-Chester Disease
- Histiocytosis, Langerhans-Cell
- Humans
- Mutation
- Phosphatidylinositol 3-Kinases
- Protein Kinase Inhibitors
- Proto-Oncogene Proteins B-raf
- Xanthogranuloma, Juvenile
