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Article

Advances in our understanding of genetic markers and targeted therapies for pediatric LCH.

Expert review of hematology - 1 Jun 2024

Bahabri Aban, Abla Oussama

Abstract excerpt

INTRODUCTION: Langerhans cell histiocytosis (LCH) is a rare myeloid neoplasm, encompassing a diverse clinical spectrum ranging from localized bone or skin lesions to a multisystemic life-threatening condition. Over the past decade, there has been an expansion in understanding the molecular biology of LCH, which translated into innovative targeted therapeutic approaches. AREAS COVERED: In this article, we will...

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Identifiers

PMID: 38721670
DOI: 10.1080/17474086.2024.2353772

Genes

BRAF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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