Efficient, robust, and versatile fluctuation data analysis using MLE MUtation Rate calculator (mlemur).

Abstract excerpt

The fluctuation assay remains an important tool for analyzing the levels of mutagenesis in microbial populations. The mutant counts originating from some average number of mutations are usually assumed to obey the Luria-Delbrück distribution. While several tools for estimating mutation rates are available, they sometimes lack accuracy or versatility under non-standard conditions. In this work, extensions to the...

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