Article
Luria-Delbrück fluctuation experiments: design and analysis.
Genetics - 1 Mar 1994
Jones M E, Thomas S M, Rogers A
Abstract excerpt
Luria and Delbrück, in a seminal paper, introduced fluctuation analysis primarily as a means to elucidate the timing of mutation in relation to the imposition of selective conditions. Their work, and subsequently that of LEA and COULSON, established also a basis for measuring the frequency of mutational events. The several estimators proposed by these authors differ both in complexity and in efficiency, and the...
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