Article
Fluctuation analysis: the probability distribution of the number of mutants under different conditions.
Genetics - 1 Jan 1990
Stewart F M, Gordon D M, Levin B R
Abstract excerpt
In the 47 years since fluctuation analysis was introduced by Luria and Delbrück, it has been widely used to calculate mutation rates. Up to now, in spite of the importance of such calculations, the probability distribution of the number of mutants that will appear in a fluctuation experiment has been known only under the restrictive, and possibly unrealistic, assumptions: (1) that the mutation rate is exactly...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.