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Article

Fluctuation analysis CalculatOR: a web tool for the determination of mutation rate using Luria-Delbruck fluctuation analysis.

Bioinformatics (Oxford, England) - 15 Jun 2009

Hall Brandon M, Ma Chang-Xing, Liang Ping, Singh Keshav K

Abstract excerpt

SUMMARY: The program Fluctuation AnaLysis CalculatOR (FALCOR) is a web tool designed for use with Luria-Delbrück fluctuation analysis to calculate the frequency and rate from various mutation assays in bacteria and yeast. Three calculation methods are available through this program: (i) Ma-Sandri-Sarkar Maximum Likelihood Estimator (MSS-MLE) method, (ii) Lea-Coulson method of the median (LC) and (iii) frequency....

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PMID: 19369502
DOI: 10.1093/bioinformatics/btp253
PMCID: PMC2687991

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