An algorithm accounting for plating efficiency in estimating spontaneous mutation rates.

doi:10.1016/0010-4825(93)90093-g

Back to search

Article

An algorithm accounting for plating efficiency in estimating spontaneous mutation rates.

Computers in biology and medicine - 1 Nov 1993

Jones M E

Abstract excerpt

An algorithm is described for calculating the probability distribution of the number of mutant colonies arising in a Luria-Delbrück fluctuation experiment subject to a plating efficiency of less than 100%. A table is constructed to facilitate the estimation of spontaneous mutation rates taking in...

Topics

Algorithms
Cells, Cultured
Clone Cells
Models, Genetic
Mutation
Probability
Selection, Genetic

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.