Article
Sample size determination for the fluctuation experiment.
Mutation research - 1 Jan 2017
Zheng Qi
Abstract excerpt
The Luria-Delbrück fluctuation experiment protocol is increasingly employed to determine microbial mutation rates in the laboratory. An important question raised at the planning stage is "How many cultures are needed?" For over 70 years sample sizes have been determined either by intuition or by following published examples where sample sizes were chosen intuitively. This paper proposes a practical method for...
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