Effects of apolipoprotein E and solute carrier organic anion transporter family member 1B1 gene polymorphisms on statin efficacy and safety in dyslipidemic patients.

doi:10.1097/FPC.0000000000000598

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Effects of apolipoprotein E and solute carrier organic anion transporter family member 1B1 gene polymorphisms on statin efficacy and safety in dyslipidemic patients.

Pharmacogenetics and genomics - 1 Jul 2026

Wu Xiaohong, Cai Yumei, Su Yonglong, Wei Xianni, Nan Tingting, Ye Xiaoyun, Lian Siheng, Wei Jinbao

Abstract excerpt

OBJECTIVE: To investigate the distribution of the apolipoprotein E ( ApoE ) and solute carrier organic anion transporter family member 1B1 ( SLCO1B1 ) polymorphisms in dyslipidemia patients and their impact on statin efficacy and safety. METHODS: A retrospective analysis was conducted on dyslipidemic inpatients (April 2024-March 2025) who received statin therapy and genetic testing for SLCO1B1 (rs4149056) and...

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Identifiers

PMID: 41861156
DOI: 10.1097/FPC.0000000000000598
PMCID: PMC13200858

Genes

SLCO1B1
APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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