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Article

Large-scale F0 CRISPR screens in vivo using MIC-Drop.

Nature protocols - 1 Jun 2023

Parvez Saba, Brandt Zachary J, Peterson Randall T

Abstract excerpt

The zebrafish is a powerful model system for studying animal development, for modeling genetic diseases, and for large-scale in vivo functional genetics. Because of its ease of use and its high efficiency in targeted gene perturbation, CRISPR-Cas9 has recently gained prominence as the tool of choice for genetic manipulation in zebrafish. However, scaling up the technique for high-throughput in vivo functional...

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PMID: 37069311
DOI: 10.1038/s41596-023-00821-y
PMCID: PMC10419324

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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