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Genetics of prostate cancer: a review of latest evidence.

Journal of medical genetics - 24 Sept 2024

Hall Rose, Bancroft Elizabeth, Pashayan Nora, Kote-Jarai Zsofia, Eeles Rosalind A

Abstract excerpt

Prostate cancer (PrCa) is a largely heritable and polygenic disease. It is the most common cancer in people with prostates (PwPs) in Europe and the USA, including in PwPs of African descent. In the UK in 2020, 52% of all cancers were diagnosed at stage I or II. The National Health Service (NHS) long-term plan is to increase this to 75% by 2028, to reduce absolute incidence of late-stage disease. In the absence of...

Topics

Humans
Prostatic Neoplasms
Male
Genetic Predisposition to Disease
Genetic Testing
Early Detection of Cancer
Genomics
Risk Factors

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 39137963
DOI: 10.1136/jmg-2024-109845

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NHS

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