Article
The relative transmission fitness of multidrug-resistant Mycobacterium tuberculosis in a drug resistance hotspot.
Nature communications - 8 Apr 2023
Loiseau Chloé, Windels Etthel M, Gygli Sebastian M, Jugheli Levan, Maghradze Nino, Brites Daniela, Ross Amanda, Goig Galo, Reinhard Miriam, Borrell Sonia, Trauner Andrej, Dötsch Anna, Aspindzelashvili Rusudan, Denes Rebecca, Reither Klaus, Beisel Christian, Tukvadze Nestani, Avaliani Zaza, Stadler Tanja, Gagneux Sebastien
Abstract excerpt
Multidrug-resistant tuberculosis (MDR-TB) is among the most frequent causes of death due to antimicrobial resistance. Although only 3% of global TB cases are MDR, geographical hotspots with up to 40% of MDR-TB have been observed in countries of the former Soviet Union. While the quality of TB control and patient-related factors are known contributors to such hotspots, the role of the pathogen remains unclear....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.