Article
Discrepancy in the transmissibility of multidrug-resistant mycobacterium tuberculosis in urban and rural areas in China.
Emerging microbes & infections - 1 Dec 2023
Li Meng, Lu Liping, Guo Mingcheng, Jiang Qi, Xia Lan, Jiang Yuan, Zhang Shu, Qiu Yong, Yang Chongguang, Chen Yiwang, Hong Jianjun, Guo Xiaoqin, Takiff Howard, Shen Xin, Chen Chuang, Gao Qian
Abstract excerpt
The fitness of multidrug-resistant tuberculosis (MDR-TB) is thought to be an important determinant of a strain's ability to be transmitted. Studies in the laboratory have demonstrated that MDR-TB strains have reduced fitness but the relative transmissibility of MDR-TB versus drug-susceptible (DS) TB strains in human populations remains unresolved. We used data on genomic clustering from our previous molecular...
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