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The host-pathogen-environment triad: Lessons learned through the study of the multidrug-resistant Mycobacterium tuberculosis M strain.

Tuberculosis (Edinburgh, Scotland) - 1 May 2022

Yokobori Noemí, López Beatriz, Ritacco Viviana

Abstract excerpt

Multidrug-resistant tuberculosis is one of the major obstacles that face the tuberculosis eradication efforts. Drug-resistant Mycobacterium tuberculosis clones were initially disregarded as a public health threat, because they were assumed to have paid a high fitness cost in exchange of resistance acquisition. However, some genotypes manage to overcome the impact of drug-resistance conferring mutations, retain...

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PMID: 35339874
DOI: 10.1016/j.tube.2022.102200

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