Article
Performance of a highly successful outbreak strain of Mycobacterium tuberculosis in a multifaceted approach to bacterial fitness assessment.
International journal of medical microbiology : IJMM - 1 Apr 2018
Yokobori Noemí, López Beatriz, Monteserin Johana, Paul Roxana, Von Groll Andrea, Martin Anandi, Marquina-Castillo Brenda, Palomino Juan Carlos, Hernández-Pando Rogelio, Sasiain María Del Carmen, Ritacco Viviana
Abstract excerpt
Determining bacterial fitness represents a major challenge and no single parameter can accurately predict the ability of a certain pathogen to succeed. The M strain of Mycobacterium tuberculosis managed to spread and establish in the community and caused the largest multidrug-resistant tuberculosis outbreak in Latin America. We have previously shown that the M strain can manipulate the host immune response, but...
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