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Article

Heterogeneity, crosstalk, and targeting of cancer-associated fibroblasts in cholangiocarcinoma

3 Jan 2023

Abstract excerpt

Cholangiocarcinoma (CCA) comprises diverse tumors of the biliary tree and is characterized by late diagnosis, short-term survival, and chemoresistance. CCAs are mainly classified according to their anatomical location and include diverse molecular subclasses harboring inter-tumoral and intratumoral heterogeneity. Besides the tumor cell component, CCA is also characterized by a complex and dynamic tumor...

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PMID: 37018128
DOI: 10.1097/hep.0000000000000206

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