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Article

Single-cell transcriptomic architecture and intercellular crosstalk of human intrahepatic cholangiocarcinoma

5 Jun 2020

Abstract excerpt

BACKGROUND & AIMS: Intrahepatic cholangiocarcinoma (ICC) is the second most common liver malignancy. ICC typically features remarkable cellular heterogeneity and a dense stromal reaction. Therefore, a comprehensive understanding of cellular diversity and the interplay between malignant cells and niche cells is essential to elucidate the mechanisms driving ICC progression and to develop therapeutic approaches....

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PMID: 32505533
DOI: 10.1016/j.jhep.2020.05.039

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