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Heterogeneity of Cholangiocarcinoma Immune Biology

8 Mar 2023

Abstract excerpt

Cholangiocarcinomas (CCAs) are aggressive tumors arising along the biliary tract epithelium, whose incidence and mortality are increasing. CCAs are highly desmoplastic cancers characterized by a dense tumor microenvironment (TME), in which each single component plays a fundamental role in shaping CCA initiation, progression and resistance to therapies. The crosstalk between cancer cells and TME can affect the...

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PMID: 36980187
DOI: 10.3390/cells12060846

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