Article

FGFR1 is a Potential Therapeutic Target in Neuroblastoma

2022-02-16

Abstract excerpt

<h4>Background: </h4> FGFR1 regulates cell-cell adhesion and extracellular matrix architecture and acts as oncogene in several cancers. Potential cancer driver mutations of FGFR1 occur in neuroblastoma NB, a neural crest-derived pediatric tumor arising in sympathetic nervous system but so far, they have not been studied experimentally. We investigated the driver-oncogene role of FGFR1 and the implication of N546K...

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Literature Corpus work: 48579603-bae3-5afb-baf1-1f9846fa79dd
DOI: 10.21203/rs.3.rs-1353035/v1

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