Article
Phenotypes Associated With Zones Defined by Area Under the Curve Glucose and C-peptide in a Population With Islet Autoantibodies.
Diabetes care - 1 May 2023
Sosenko Jay M, Cuthbertson David, Sims Emily K, Ismail Heba M, Nathan Brandon M, Jacobsen Laura M, Atkinson Mark A, Evans-Molina Carmella, Herold Kevan C, Skyler Jay S, Redondo Maria J
Abstract excerpt
OBJECTIVE: Metabolic zones were developed to characterize heterogeneity of individuals with islet autoantibodies. RESEARCH DESIGN AND METHODS: Baseline 2-h oral glucose tolerance test data from 6,620 TrialNet Pathway to Prevention Study (TNPTP) autoantibody-positive participants (relatives of individuals with type 1 diabetes) were used to form 25 zones from five area under the curve glucose (AUCGLU) rows and five...
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