Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterising the age-dependent effects of risk factors on type 1 diabetes progression.

Diabetologia - 1 Apr 2022

So Michelle, O'Rourke Colin, Ylescupidez Alyssa, Bahnson Henry T, Steck Andrea K, Wentworth John M, Bruggeman Brittany S, Lord Sandra, Greenbaum Carla J, Speake Cate

Abstract excerpt

AIMS/HYPOTHESIS: Age is known to be one of the most important stratifiers of disease progression in type 1 diabetes. However, what drives the difference in rate of progression between adults and children is poorly understood. Evidence suggests that many type 1 diabetes disease predictors do not have the same effect across the age spectrum. Without a comprehensive analysis describing the varying risk profiles of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoantibodies
Share to Child, Preschool

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 1

Share to Disease Progression

Share to HLA-DR3 Antigen

Share to Infant

Share to Risk Factors

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 35041021
DOI: 10.1007/s00125-021-05647-5
PMCID: PMC9928893

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterising the age-dependent effects of risk factors on type 1 diabetes progression.PMID 35041021Read ↗

The risk of progression to type 1 diabetes is highly variable in individuals with multiple autoantibodies following screening.Semantic proximity Read ↗

Genetic Risk and Transition Through Preclinical Stages of Type 1 Diabetes.Semantic proximity Read ↗

A Type 1 Diabetes Genetic Risk Score Predicts Progression of Islet Autoimmunity and Development of Type 1 Diabetes in Individuals at Risk.Semantic proximity Read ↗

Data-Driven Phenotyping of Presymptomatic Type 1 Diabetes Using Longitudinal Autoantibody Profiles.Semantic proximity Read ↗

Ethnic differences in progression of islet autoimmunity and type 1 diabetes in relatives at risk.Semantic proximity Read ↗

Precision Diagnostics: Using Islet Autoantibodies to Characterize Heterogeneity in Type 1 DiabetesSemantic proximity Read ↗

Novel genetic risk factors influence progression of islet autoimmunity to type 1 diabetes.Semantic proximity Read ↗

Progression of type 1 diabetes from latency to symptomatic disease is predicted by distinct autoimmune trajectories.Semantic proximity Read ↗

Progression from islet autoimmunity to clinical type 1 diabetes is influenced by genetic factors: results from the prospective TEDDY study.Semantic proximity Read ↗

Twenty-Year Progression Rate to Clinical Onset According to Autoantibody Profile, Age, and HLA-DQ Genotype in a Registry-Based Group of Children and Adults With a First-Degree Relative With Type 1 DiabetesSemantic proximity Read ↗

Extending the Eisenbarth Model: Stage 0 as a Provisional Framework for Early Risk Stratification and Prevention in Type 1 Diabetes.Semantic proximity Read ↗

Risk of beta-cell autoimmunity presence for progression to type 1 diabetes: A systematic review and meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.