Article
Identification of type 1 diabetes risk phenotypes using an outcome-guided clustering analysis.
Diabetologia - 1 Nov 2024
You Lu, Ferrat Lauric A, Oram Richard A, Parikh Hemang M, Steck Andrea K, Krischer Jeffrey, Redondo Maria J
Abstract excerpt
AIMS/HYPOTHESIS: Although statistical models for predicting type 1 diabetes risk have been developed, approaches that reveal the heterogeneity of the at-risk population by identifying clinically meaningful clusters are lacking. We aimed to identify and characterise clusters of islet autoantibody-positive individuals who share similar characteristics and type 1 diabetes risk. METHODS: We tested a novel...
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