Article
Association of inducible nitric oxide synthase with asthma severity, total serum immunoglobulin E and blood eosinophil levels.
Thorax - 1 Jan 2007
Batra Jyotsna, Pratap Singh Tej, Mabalirajan Ulanganathan, Sinha Aditi, Prasad Rajendra, Ghosh Balaram
Abstract excerpt
BACKGROUND: Nitric oxide is released by immune, epithelial and endothelial cells, and plays an important part in the pathophysiology of asthma. OBJECTIVE: To investigate the association of inducible nitric oxide synthases (iNOS) gene repeat polymorphisms with asthma. METHODS: 230 families with asthma (842 individuals) were recruited to identify and establish the genetic association of iNOS repeats with asthma and...
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